A suppressor T cell in the human mixed lymphocyte reaction
نویسندگان
چکیده
Lymphocytes from an HLA-B7 DW2 homozygous multiparous woman, J.H., failed to respond in the mixed lymphocyte reaction to lymphocytes from her DW1 homozygous husband, W.H., and certain other homozygous typing cells. J.H. lymphocytes could suppress the response of HLA matched responders to W.H. This effect was shown to be radiosensitive and due to a T cell. The suppressor cell showed antigen specificity.
منابع مشابه
A suppressor T cell of the mixed lymphocyte reaction in man specific for the stimulating alloantigen. Evidence that identity at HLA-D between suppressor and responder is required for suppression
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 146 شماره
صفحات -
تاریخ انتشار 1977